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Polynucleotides

Polynucleotide therapy is an advanced injectable treatment designed to repair, strengthen, and revitalise the skin from within — delivering natural, long-lasting rejuvenation without adding volume or altering your natural features.

What are Polynucleotides?

Polynucleotides are highly purified DNA fragments that work as powerful bio-stimulators within the skin.

Once injected, they activate the body’s natural healing response, stimulating collagen and elastin production while improving hydration and skin quality.

This results in firmer, smoother, and more radiant skin — achieved through regeneration rather than artificial enhancement.

How Polynucleotide Treatment Works

Polynucleotides support skin regeneration by:

  • Stimulating fibroblast activity (collagen-producing cells)

  • Enhancing skin hydration and elasticity

  • Repairing damaged or ageing tissue

  • Improving microcirculation and overall skin health

The treatment works progressively, allowing your skin to rebuild itself naturally over time.

Treatment Overview

Treatment Time: 30–45 minutes

Downtime: Minimal

Return to Activities: Same day

Results: Typically visible 2–4 weeks after a course of treatments

What Can It Treat?

Polynucleotide therapy is ideal for:

  • Dull, tired or ageing skin

  • Fine lines and early wrinkles

  • Loss of elasticity and firmness

  • Under-eye concerns (dark circles, crepey skin)

  • Skin dehydration and poor texture

Suitable treatment areas include:

  • Face

  • Neck

  • Décolletage

  • Under-eye area

Benefits of Polynucleotides

  • Stimulates natural collagen and elastin production

  • Improves skin hydration and elasticity

  • Enhances skin texture and smoothness

  • Reduces fine lines and early signs of ageing

  • Promotes skin healing and regeneration

  • Delivers subtle, natural-looking rejuvenation

  • Maintains facial harmony without adding volume

Your Treatment Experience at SHR

Your journey begins with a personalised consultation to assess your skin and create a bespoke treatment plan tailored to your goals.

The treatment is performed using advanced, precise techniques to ensure comfort, safety, and optimal results.

Results & Longevity

You may notice improvements in skin hydration and radiance within the first few weeks, with continued enhancement in firmness and texture over time.

For optimal results, a course of treatments is recommended, followed by maintenance sessions to sustain your results.

Who is This Treatment For?

Polynucleotide therapy is suitable for most skin types and is ideal for individuals seeking natural, regenerative skin rejuvenation without fillers or invasive procedures.

Price starts from £180 depending on treatment area.

After Care Plan:

 

Congratulations on your Polynucleotide treatment at SHR Medical Aesthetics. Following these guidelines will help you achieve optimal results and minimize the risk of complications. Please read these instructions carefully.

 

Immediate Aftercare (First 4 Hours):

Avoid Touching the Treated Area: Refrain from touching, rubbing, or massaging the injection sites to prevent potential irritation or infection.

No Makeup: Refrain from applying makeup to the treated area for at least 6 hours, preferably until the next day.

 

Side Effects:

Mild redness, swelling, and small bumps at the injection sites are normal.

Mild tenderness or sensitivity at the injection sites may occur.

Bruising is possible and will resolve in a few days.

 

First 24 Hours (Day One):

Stay Cool: Avoid heat exposure such as saunas, hot tubs, and hot showers. Also avoid strenuous exercise that could cause you to sweat.

Avoid Pressure: Don’t sleep on the treated area. Try to sleep on your back if you can.

Hydrate: Drink plenty of water.

Alcohol and Blood Thinners: Avoid alcohol consumption as well as any other blood thinners (aspirin, ibuprofen, etc.)

 

Next 2 Weeks (Days 2-14):

Gentle Skincare: Use a gentle cleanser and moisturizer. Avoid harsh exfoliants or active ingredients (retinoids, AHAs, BHAs).

Sun Protection: Protect your skin from sun exposure by using a high SPF sunscreen (SPF 30 or higher).

Continue to Avoid: Continue to avoid excessive heat and strenuous exercise.

Be Patient: Remember that results develop gradually. You may not see any difference right away, improvements will appear over the coming weeks and months.

Avoid Facial Treatments: Refrain from facials or massages in the treated area.

 

What to Expect:

Gradual Improvement: Polynucleotides stimulate natural collagen and elastin production, so the improvements in skin texture and hydration are gradual over weeks and months.

Temporary Side Effects: Any redness, swelling, or bruising is temporary and should resolve within a few days.

 

When to Contact Us:

Seek medical assistance immediately if you experience:

-      Severe pain at injection sites.

-      Signs of infection (increased redness, swelling, warmth, pus).

-      Allergic reaction (difficulty breathing, hives, severe swelling).

-      Persistent swelling lasting more than a few days.

Contact us for any other concerns about the treatment or your recovery.

 

Important Notes:

This aftercare guide is for general advice. Your practitioner may provide additional instructions specific to your treatment. Please always follow their specific recommendations.

Please contact us for a free consultation, pricing and therapy appointment(s)

*** Appointments are subject to £50 redeemable deposit ***

Myths vs Reality

1. What are Polynucleotides?

Reality: Natural DNA fragments that stimulate collagen & elastin production

2. Is it just for wrinkles?

Reality: Treats hydration, texture, acne scars, and skin rejuvenation

3. How many sessions needed?

Typically 3-4 sessions, spaced 4-6 weeks apart

4. Is it painful?

Minimal discomfort - we usually apply a topical numbing cream for extra comfort

5. How long do results last?

6-12 months; maintenance sessions recommended

6. Can I combine with other treatments?

Yes, often paired with microneedling or similar therapies

*** Kindly note, that all our therapies are provided for wellness and aesthetic enhancement and are not intended to replace medical care. We recommend consulting your GP or healthcare provider for any medical concerns prior to treatment, especially for those suffering with ongoing health issues, pregnancy or on critical medication ***